Module 18 Activity Worksheet

Module

Module 18: Data Cleaning and Preprocessing

Capability Target

Produce a reproducible preprocessing release that transforms raw or intermediate connectomics outputs into analysis-ready data, with explicit quality gates and full provenance.

Studio Activity Instructions

Evidence and Reasoning Notes

• Claim:
• Evidence:
• Limitation:

Rubric Check

• Minimum pass
  • Cleaning decisions are explicit and reproducible.
  • QC metrics include thresholds tied to actions.
  • Release package includes provenance metadata.
• Strong performance
  • Distinguishes low-risk cleanup from biologically sensitive transforms.
  • Quantifies and explains pre/post changes clearly.
  • Documents limitations and unresolved risks transparently.
• Common failure modes
  • Silent ad-hoc edits with no transform log.
  • Aggressive filtering that removes biologically meaningful variation.
  • Metrics reported without operational thresholds.

Exit Prompt

Take one connectomics table (real or mock) and write:

1. Three cleaning rules with rationale.
2. Two QC thresholds and associated actions.
3. One limitation that remains after preprocessing.