Module 04: Neuroanatomy for Connectomics

Teaching Deck

Learning Objectives

  • Identify major neuroanatomical compartments relevant to connectomics
  • Relate anatomical context to interpretation of local EM structures
  • Use region/layer context to avoid misclassification
  • Communicate anatomy-based uncertainty clearly

Session Outcomes

  • Learners can complete the module capability target.
  • Learners can produce one evidence-backed artifact.
  • Learners can state one limitation or uncertainty.

Agenda (60 min)

  • 0-10 min: Frame and model
  • 10-35 min: Guided practice
  • 35-50 min: Debrief and misconception correction
  • 50-60 min: Competency check + exit ticket

Capability Target

Interpret a local EM region using correct anatomical context and document one confident and one uncertain structural call.

Concept Focus

  • Region/layer context affects interpretation.
  • Local morphology needs cross-slice and cross-region checks.
  • Uncertainty should be explicit when anatomy is ambiguous.

Core Workflow

  • Identify anatomical region/layer.
  • Map candidate structures to known context.
  • Cross-check with neighboring slices.
  • Annotate confidence and escalation path.

60-Minute Run-of-Show

  • 00:00-10: macro-to-micro anatomy bridge.
  • 10:00-24: guided structural identification.
  • 24:00-38: ambiguity case discussion.
  • 38:00-50: learner annotation round.
  • 50:00-60: debrief and competency check.

Misconceptions to Watch

  • Surface and correct one likely misconception during debrief.

Studio Activity

Label one patch set with anatomy context, structure call, and confidence rationale.

Activity Output Checklist

  • Evidence-linked artifact submitted.
  • At least one limitation or uncertainty stated.
  • Revision point captured from feedback.

Assessment Rubric

  • Minimum: context-aware call and confidence note.
  • Strong: clear rationale with cross-slice checks.
  • Failure: isolated local cue overconfidence.

Exit Ticket

Describe one case where anatomy context changes your interpretation.

References (Instructor)

  • Use module references listed on the module page.

Teaching Materials

  • Module page: /modules/module04/
  • Slide page: /modules/slides/module04/
  • Worksheet: /assets/worksheets/module04/module04-activity.md